STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S4RNX8_PETMA26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (680 aa)    
Predicted Functional Partners:
S4R7Q9_PETMA
AAA domain-containing protein; Belongs to the AAA ATPase family.
   
 0.999
S4R8Q0_PETMA
Proteasome 26S subunit, non-ATPase 12.
   
 0.999
S4RAN3_PETMA
PCI domain-containing protein.
   
 0.999
S4RDQ3_PETMA
Proteasome 26S subunit, non-ATPase 4a.
   
 0.999
S4REN7_PETMA
Proteasome 26S subunit, non-ATPase 3.
   
 0.999
S4RGK0_PETMA
Proteasome 26S subunit, non-ATPase 8.
   
 0.999
S4RGQ0_PETMA
Proteasome 26S subunit, non-ATPase 14.
   
 0.999
S4RHU9_PETMA
Proteasome 26S subunit, non-ATPase 2.
   
 0.999
KATNAL2
Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
   
 0.999
S4RNK7_PETMA
Proteasome 26S subunit, ATPase 1a.
   
 0.999
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.