DNMT3A protein (Petromyzon marinus) - STRING interaction network

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Score

DNMT3A

DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (419 aa)

Predicted Functional Partners:

DNMT1

0.911

S4RAY1_PETMA

0.896

S4RI70_PETMA

0.829

S4RRF9_PETMA

0.798

S4RXI3_PETMA

0.787

S4R9E4_PETMA

0.710

S4RMT0_PETMA

0.687

S4RZ66_PETMA

0.656

S4RV40_PETMA

0.649

S4RXT2_PETMA

0.649

Your Current Organism:

Petromyzon marinus

NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DNMT1	DNMT3A	ENSPMAP00000002859	ENSPMAP00000007594	DNA methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.911
DNMT1	S4R9E4_PETMA	ENSPMAP00000002859	ENSPMAP00000001825	DNA methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Embryonic ectoderm development.	0.752
DNMT1	S4RAY1_PETMA	ENSPMAP00000002859	ENSPMAP00000002362	DNA methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Uncharacterized protein.	0.947
DNMT1	S4RI70_PETMA	ENSPMAP00000002859	ENSPMAP00000004902	DNA methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Uncharacterized protein.	0.878
DNMT1	S4RRF9_PETMA	ENSPMAP00000002859	ENSPMAP00000007795	DNA methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family.	0.800
DNMT1	S4RV40_PETMA	ENSPMAP00000002859	ENSPMAP00000009080	DNA methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Hist_deacetyl domain-containing protein.	0.742
DNMT1	S4RXI3_PETMA	ENSPMAP00000002859	ENSPMAP00000009924	DNA methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.	0.845
DNMT1	S4RXT2_PETMA	ENSPMAP00000002859	ENSPMAP00000010023	DNA methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.742
DNMT1	S4RZ66_PETMA	ENSPMAP00000002859	ENSPMAP00000010507	DNA methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	SUZ12 polycomb repressive complex 2 subunit a.	0.687
DNMT3A	DNMT1	ENSPMAP00000007594	ENSPMAP00000002859	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	DNA methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.911
DNMT3A	S4R9E4_PETMA	ENSPMAP00000007594	ENSPMAP00000001825	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Embryonic ectoderm development.	0.710
DNMT3A	S4RAY1_PETMA	ENSPMAP00000007594	ENSPMAP00000002362	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Uncharacterized protein.	0.896
DNMT3A	S4RI70_PETMA	ENSPMAP00000007594	ENSPMAP00000004902	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Uncharacterized protein.	0.829
DNMT3A	S4RMT0_PETMA	ENSPMAP00000007594	ENSPMAP00000006516	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Protein kinase domain-containing protein.	0.687
DNMT3A	S4RRF9_PETMA	ENSPMAP00000007594	ENSPMAP00000007795	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family.	0.798
DNMT3A	S4RV40_PETMA	ENSPMAP00000007594	ENSPMAP00000009080	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Hist_deacetyl domain-containing protein.	0.649
DNMT3A	S4RXI3_PETMA	ENSPMAP00000007594	ENSPMAP00000009924	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.	0.787
DNMT3A	S4RXT2_PETMA	ENSPMAP00000007594	ENSPMAP00000010023	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.649
DNMT3A	S4RZ66_PETMA	ENSPMAP00000007594	ENSPMAP00000010507	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	SUZ12 polycomb repressive complex 2 subunit a.	0.656
S4R9E4_PETMA	DNMT1	ENSPMAP00000001825	ENSPMAP00000002859	Embryonic ectoderm development.	DNA methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.752