node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCM2 | MCM7 | ENSPMAP00000005297 | ENSPMAP00000005986 | Minichromosome maintenance complex component 2. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
MCM2 | S4RAX6_PETMA | ENSPMAP00000005297 | ENSPMAP00000002357 | Minichromosome maintenance complex component 2. | Minichromosome maintenance complex component 5; Belongs to the MCM family. | 0.999 |
MCM2 | S4RKL0_PETMA | ENSPMAP00000005297 | ENSPMAP00000005743 | Minichromosome maintenance complex component 2. | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM2 | S4RLY7_PETMA | ENSPMAP00000005297 | ENSPMAP00000006223 | Minichromosome maintenance complex component 2. | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. | 0.998 |
MCM2 | S4RNJ7_PETMA | ENSPMAP00000005297 | ENSPMAP00000006783 | Minichromosome maintenance complex component 2. | WD repeat and HMG-box DNA binding protein 1. | 0.998 |
MCM2 | S4RS67_PETMA | ENSPMAP00000005297 | ENSPMAP00000008056 | Minichromosome maintenance complex component 2. | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. | 0.992 |
MCM2 | S4RSD9_PETMA | ENSPMAP00000005297 | ENSPMAP00000008128 | Minichromosome maintenance complex component 2. | MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like; Belongs to the MCM family. | 0.999 |
MCM2 | S4RWI9_PETMA | ENSPMAP00000005297 | ENSPMAP00000009579 | Minichromosome maintenance complex component 2. | Piezo_RRas_bdg domain-containing protein. | 0.937 |
MCM2 | S4RXG6_PETMA | ENSPMAP00000005297 | ENSPMAP00000009907 | Minichromosome maintenance complex component 2. | Timeless circadian clock. | 0.992 |
MCM2 | S4RZP9_PETMA | ENSPMAP00000005297 | ENSPMAP00000010690 | Minichromosome maintenance complex component 2. | GINS complex subunit 1 (Psf1 homolog). | 0.997 |
MCM7 | MCM2 | ENSPMAP00000005986 | ENSPMAP00000005297 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Minichromosome maintenance complex component 2. | 0.999 |
MCM7 | S4RAX6_PETMA | ENSPMAP00000005986 | ENSPMAP00000002357 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Minichromosome maintenance complex component 5; Belongs to the MCM family. | 0.999 |
MCM7 | S4RKL0_PETMA | ENSPMAP00000005986 | ENSPMAP00000005743 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | S4RLY7_PETMA | ENSPMAP00000005986 | ENSPMAP00000006223 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. | 0.988 |
MCM7 | S4RNJ7_PETMA | ENSPMAP00000005986 | ENSPMAP00000006783 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | WD repeat and HMG-box DNA binding protein 1. | 0.992 |
MCM7 | S4RS67_PETMA | ENSPMAP00000005986 | ENSPMAP00000008056 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. | 0.988 |
MCM7 | S4RSD9_PETMA | ENSPMAP00000005986 | ENSPMAP00000008128 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like; Belongs to the MCM family. | 0.999 |
MCM7 | S4RWI9_PETMA | ENSPMAP00000005986 | ENSPMAP00000009579 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Piezo_RRas_bdg domain-containing protein. | 0.568 |
MCM7 | S4RXG6_PETMA | ENSPMAP00000005986 | ENSPMAP00000009907 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Timeless circadian clock. | 0.980 |
MCM7 | S4RZP9_PETMA | ENSPMAP00000005986 | ENSPMAP00000010690 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | GINS complex subunit 1 (Psf1 homolog). | 0.995 |