STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S4RSD5_PETMAVPS8 subunit of CORVET complex. (1383 aa)    
Predicted Functional Partners:
S4RHG0_PETMA
VPS18 core subunit of CORVET and HOPS complexes.
    
 
 0.995
S4RXC1_PETMA
Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.
    
 
 0.995
S4RSG4_PETMA
VPS39 subunit of HOPS complex.
   
 
 0.980
S4RM90_PETMA
VPS33A core subunit of CORVET and HOPS complexes; Belongs to the STXBP/unc-18/SEC1 family.
    
 
 0.960
S4RFL9_PETMA
VPS33B late endosome and lysosome associated; Belongs to the STXBP/unc-18/SEC1 family.
    
 
 0.957
S4RIT6_PETMA
Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.
   
 
 0.728
S4R480_PETMA
RAB5C, member RAS oncogene family.
    
 
 0.672
RAB31
RAB31, member RAS oncogene family.
    
 
 0.672
S4R8L0_PETMA
Uncharacterized protein.
    
 
 0.672
S4R8L4_PETMA
Uncharacterized protein.
    
 
 0.672
Your Current Organism:
Petromyzon marinus
NCBI taxonomy Id: 7757
Other names: P. marinus, marine lamprey, sea lamprey, sea lampreys
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.