node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCM2 | MCM7 | ENSPMAP00000005297 | ENSPMAP00000005986 | Minichromosome maintenance complex component 2. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.999 |
MCM2 | S4RAX6_PETMA | ENSPMAP00000005297 | ENSPMAP00000002357 | Minichromosome maintenance complex component 2. | Minichromosome maintenance complex component 5; Belongs to the MCM family. | 0.999 |
MCM2 | S4REU4_PETMA | ENSPMAP00000005297 | ENSPMAP00000003726 | Minichromosome maintenance complex component 2. | MCM domain-containing protein. | 0.994 |
MCM2 | S4RKL0_PETMA | ENSPMAP00000005297 | ENSPMAP00000005743 | Minichromosome maintenance complex component 2. | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM2 | S4RNJ7_PETMA | ENSPMAP00000005297 | ENSPMAP00000006783 | Minichromosome maintenance complex component 2. | WD repeat and HMG-box DNA binding protein 1. | 0.998 |
MCM2 | S4RSD9_PETMA | ENSPMAP00000005297 | ENSPMAP00000008128 | Minichromosome maintenance complex component 2. | MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like; Belongs to the MCM family. | 0.999 |
MCM2 | S4RU69_PETMA | ENSPMAP00000005297 | ENSPMAP00000008759 | Minichromosome maintenance complex component 2. | Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. | 0.995 |
MCM2 | S4RWL2_PETMA | ENSPMAP00000005297 | ENSPMAP00000009602 | Minichromosome maintenance complex component 2. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.999 |
MCM2 | S4RXB0_PETMA | ENSPMAP00000005297 | ENSPMAP00000009850 | Minichromosome maintenance complex component 2. | Origin recognition complex, subunit 2. | 0.999 |
MCM2 | S4RZP9_PETMA | ENSPMAP00000005297 | ENSPMAP00000010690 | Minichromosome maintenance complex component 2. | GINS complex subunit 1 (Psf1 homolog). | 0.997 |
MCM7 | MCM2 | ENSPMAP00000005986 | ENSPMAP00000005297 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Minichromosome maintenance complex component 2. | 0.999 |
MCM7 | S4RAX6_PETMA | ENSPMAP00000005986 | ENSPMAP00000002357 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Minichromosome maintenance complex component 5; Belongs to the MCM family. | 0.999 |
MCM7 | S4REU4_PETMA | ENSPMAP00000005986 | ENSPMAP00000003726 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | MCM domain-containing protein. | 0.994 |
MCM7 | S4RKL0_PETMA | ENSPMAP00000005986 | ENSPMAP00000005743 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | DNA helicase; Belongs to the MCM family. | 0.999 |
MCM7 | S4RNJ7_PETMA | ENSPMAP00000005986 | ENSPMAP00000006783 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | WD repeat and HMG-box DNA binding protein 1. | 0.992 |
MCM7 | S4RSD9_PETMA | ENSPMAP00000005986 | ENSPMAP00000008128 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like; Belongs to the MCM family. | 0.999 |
MCM7 | S4RU69_PETMA | ENSPMAP00000005986 | ENSPMAP00000008759 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. | 0.994 |
MCM7 | S4RWL2_PETMA | ENSPMAP00000005986 | ENSPMAP00000009602 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.999 |
MCM7 | S4RXB0_PETMA | ENSPMAP00000005986 | ENSPMAP00000009850 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Origin recognition complex, subunit 2. | 0.998 |
MCM7 | S4RZP9_PETMA | ENSPMAP00000005986 | ENSPMAP00000010690 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | GINS complex subunit 1 (Psf1 homolog). | 0.995 |