STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BISU_0084Membrane protein. (242 aa)    
Predicted Functional Partners:
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
    0.818
BISU_0081
Zn-ribbon-containing RNA-binding protein.
 
     0.739
BISU_0617
Hypothetical protein.
  
     0.734
rbpA
Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
  
     0.711
BISU_0969
Membrane protein.
  
     0.701
BISU_1100
Hypothetical protein.
  
     0.699
BISU_1436
Hypothetical protein.
  
     0.699
BISU_0124
Trehalose 6-phosphate synthase/phosphatase.
   
    0.694
BISU_0085
Teicoplanin resistance protein VanZ.
       0.685
BISU_0622
ATP-binding protein.
  
     0.683
Your Current Organism:
Bifidobacterium subtile
NCBI taxonomy Id: 77635
Other names: AS 1.2267, ATCC 27537, B. subtile, BCRC 14660, CCRC 14660, CCRC:14660, CCUG 34980, DSM 20096, JCM 5822, LMG 11597, LMG:11597
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.