STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BISU_0159Peptidase. (689 aa)    
Predicted Functional Partners:
arc
ATPase AAA.
    
 0.858
tgt
Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]
       0.677
rpsF
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
   
 
 0.652
BISU_1735
Trypsin-like serine protease; Belongs to the peptidase S1B family.
     
 0.633
rplK
50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
   0.630
BISU_0486
Membrane protein.
    
 
 0.628
rplI
50S ribosomal protein L9; Binds to the 23S rRNA.
 
 
   0.616
BISU_1649
Histidine kinase sensor of two component system.
  
  
 0.576
BISU_0334
Secreted peptidyl-prolyl cis-trans isomerase protein.
   
 
 0.562
BISU_0525
Peptidyl-prolyl cis-trans isomerase.
   
 
 0.562
Your Current Organism:
Bifidobacterium subtile
NCBI taxonomy Id: 77635
Other names: AS 1.2267, ATCC 27537, B. subtile, BCRC 14660, CCRC 14660, CCRC:14660, CCUG 34980, DSM 20096, JCM 5822, LMG 11597, LMG:11597
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.