STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (382 aa)    
Predicted Functional Partners:
BISU_0766
Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 
 0.980
BISU_0946
Glutamate synthase.
    
  0.897
ftsH
Cell division protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
 
   
 0.892
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.854
BISU_0768
D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase.
     
 0.827
BISU_0265
Thiamine biosynthesis protein ThiS.
  
   0.788
BISU_0227
IMP dehydrogenase family protein.
  
 
  0.763
guaB
IMP dehydrogenase/GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
  0.763
truA
50S ribosomal protein L17; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
  
 
 0.743
BISU_1807
Inosine 5'-monophosphate dehydrogenase.
  
 
  0.737
Your Current Organism:
Bifidobacterium subtile
NCBI taxonomy Id: 77635
Other names: AS 1.2267, ATCC 27537, B. subtile, BCRC 14660, CCRC 14660, CCRC:14660, CCUG 34980, DSM 20096, JCM 5822, LMG 11597, LMG:11597
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