STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Xaut_0366PFAM: aldehyde dehydrogenase; KEGG: bme:BMEI1747 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (506 aa)    
Predicted Functional Partners:
Xaut_1859
PFAM: AMP-dependent synthetase and ligase; KEGG: pfo:Pfl_2870 AMP-dependent synthetase and ligase.
  
 0.938
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.934
Xaut_2096
PFAM: AMP-dependent synthetase and ligase; KEGG: rle:RL4301 putative acetyl-coenzyme A synthetase.
  
 0.934
Xaut_3527
PFAM: AMP-dependent synthetase and ligase; KEGG: bbt:BBta_6789 acetyl-coenzyme A synthetase.
  
 0.934
Xaut_2610
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMc03929 putative zinc-type alcohol dehydrogenase transmembrane protein.
 
 0.924
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
 
 
 0.921
Xaut_1357
PFAM: aldehyde dehydrogenase; KEGG: bra:BRADO5849 NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.917
Xaut_2010
TIGRFAM: Alcohol dehydrogenase zinc-binding type 2; PFAM: oxidoreductase domain protein; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bov:BOV_1026 alcohol dehydrogenase, zinc-containing.
  
 
 0.917
Xaut_1730
PFAM: acetyl-CoA hydrolase/transferase; KEGG: rru:Rru_A1927 acetyl-CoA hydrolase.
  
 
 0.912
Xaut_0937
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
    
 0.909
Your Current Organism:
Xanthobacter autotrophicus
NCBI taxonomy Id: 78245
Other names: X. autotrophicus Py2, Xanthobacter autotrophicus Py2, Xanthobacter autotrophicus str. Py2, Xanthobacter autotrophicus strain Py2, Xanthobacter sp. Py2
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.