STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Xaut_0448KEGG: sme:SMc00395 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase. (220 aa)    
Predicted Functional Partners:
mtnK
5-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
     
 0.926
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
 0.922
Xaut_2119
PFAM: Spermine synthase; KEGG: bra:BRADO6330 putative spermine/spermidine synthase family protein.
    
 0.907
Xaut_3699
PFAM: C-5 cytosine-specific DNA methylase; KEGG: mlo:mlr8517 modification methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
    
  0.902
Xaut_0447
PFAM: Fmu (Sun) domain protein; KEGG: rpb:RPB_3190 RNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.807
Xaut_0449
KEGG: rpc:RPC_3065 protein of unknown function DUF1123.
       0.558
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
   
 
 0.543
Xaut_1816
PFAM: S-adenosylmethionine synthetase; KEGG: rpe:RPE_4204 methionine adenosyltransferase; Belongs to the AdoMet synthase family.
  
 
 0.542
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.509
Xaut_2832
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.486
Your Current Organism:
Xanthobacter autotrophicus
NCBI taxonomy Id: 78245
Other names: X. autotrophicus Py2, Xanthobacter autotrophicus Py2, Xanthobacter autotrophicus str. Py2, Xanthobacter autotrophicus strain Py2, Xanthobacter sp. Py2
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