node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Xaut_1203 | Xaut_3524 | Xaut_1203 | Xaut_3524 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bbt:BBta_0839 threonine synthase. | 0.961 |
Xaut_1203 | pdxA | Xaut_1203 | Xaut_2834 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.920 |
Xaut_1420 | pdxA | Xaut_1420 | Xaut_2834 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.718 |
Xaut_2835 | Xaut_2837 | Xaut_2835 | Xaut_2837 | KEGG: nwi:Nwi_1680 putative peptidyl-prolyl cis-trans isomerase SurA. | PFAM: permease YjgP/YjgQ family protein; KEGG: nwi:Nwi_1678 permease YjgP/YjgQ. | 0.573 |
Xaut_2835 | lptD | Xaut_2835 | Xaut_2836 | KEGG: nwi:Nwi_1680 putative peptidyl-prolyl cis-trans isomerase SurA. | Organic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family. | 0.853 |
Xaut_2835 | pdxA | Xaut_2835 | Xaut_2834 | KEGG: nwi:Nwi_1680 putative peptidyl-prolyl cis-trans isomerase SurA. | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.656 |
Xaut_2835 | rsmA | Xaut_2835 | Xaut_2833 | KEGG: nwi:Nwi_1680 putative peptidyl-prolyl cis-trans isomerase SurA. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.734 |
Xaut_2837 | Xaut_2835 | Xaut_2837 | Xaut_2835 | PFAM: permease YjgP/YjgQ family protein; KEGG: nwi:Nwi_1678 permease YjgP/YjgQ. | KEGG: nwi:Nwi_1680 putative peptidyl-prolyl cis-trans isomerase SurA. | 0.573 |
Xaut_2837 | lptD | Xaut_2837 | Xaut_2836 | PFAM: permease YjgP/YjgQ family protein; KEGG: nwi:Nwi_1678 permease YjgP/YjgQ. | Organic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family. | 0.942 |
Xaut_2837 | pdxA | Xaut_2837 | Xaut_2834 | PFAM: permease YjgP/YjgQ family protein; KEGG: nwi:Nwi_1678 permease YjgP/YjgQ. | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.423 |
Xaut_2837 | rsmA | Xaut_2837 | Xaut_2833 | PFAM: permease YjgP/YjgQ family protein; KEGG: nwi:Nwi_1678 permease YjgP/YjgQ. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.444 |
Xaut_3524 | Xaut_1203 | Xaut_3524 | Xaut_1203 | TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bbt:BBta_0839 threonine synthase. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.961 |
Xaut_3524 | pdxA | Xaut_3524 | Xaut_2834 | TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bbt:BBta_0839 threonine synthase. | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.905 |
Xaut_3524 | ribB | Xaut_3524 | Xaut_4136 | TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bbt:BBta_0839 threonine synthase. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.402 |
gyrB | pdxA | Xaut_1873 | Xaut_2834 | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.713 |
gyrB | rsmA | Xaut_1873 | Xaut_2833 | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.420 |
lptD | Xaut_2835 | Xaut_2836 | Xaut_2835 | Organic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family. | KEGG: nwi:Nwi_1680 putative peptidyl-prolyl cis-trans isomerase SurA. | 0.853 |
lptD | Xaut_2837 | Xaut_2836 | Xaut_2837 | Organic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family. | PFAM: permease YjgP/YjgQ family protein; KEGG: nwi:Nwi_1678 permease YjgP/YjgQ. | 0.942 |
lptD | pdxA | Xaut_2836 | Xaut_2834 | Organic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family. | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). | 0.450 |
lptD | rsmA | Xaut_2836 | Xaut_2833 | Organic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.648 |