| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Xaut_0075 | Xaut_3208 | Xaut_0075 | Xaut_3208 | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rpa:RPA0557 cysteine synthase, cytosolic O-acetylserine(thiol)lyase. | TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein; KEGG: rpa:RPA3429 serine acetyltransferase. | 0.989 |
| Xaut_0075 | Xaut_3521 | Xaut_0075 | Xaut_3521 | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rpa:RPA0557 cysteine synthase, cytosolic O-acetylserine(thiol)lyase. | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: rpa:RPA2504 homoserine dehydrogenase. | 0.455 |
| Xaut_0075 | Xaut_4677 | Xaut_0075 | Xaut_4677 | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rpa:RPA0557 cysteine synthase, cytosolic O-acetylserine(thiol)lyase. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: rpc:RPC_2553 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | 0.916 |
| Xaut_0871 | Xaut_1506 | Xaut_0871 | Xaut_1506 | TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: acr:Acry_0996 L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: threonine dehydratase. | 0.922 |
| Xaut_0871 | Xaut_1660 | Xaut_0871 | Xaut_1660 | TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: acr:Acry_0996 L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: rpc:RPC_3257 phosphoserine phosphatase SerB. | 0.914 |
| Xaut_0871 | Xaut_3208 | Xaut_0871 | Xaut_3208 | TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: acr:Acry_0996 L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein; KEGG: rpa:RPA3429 serine acetyltransferase. | 0.909 |
| Xaut_0871 | Xaut_3521 | Xaut_0871 | Xaut_3521 | TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: acr:Acry_0996 L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: rpa:RPA2504 homoserine dehydrogenase. | 0.816 |
| Xaut_0871 | Xaut_4110 | Xaut_0871 | Xaut_4110 | TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: acr:Acry_0996 L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bra:BRADO5091 putative threonine dehydratase. | 0.922 |
| Xaut_0871 | Xaut_4294 | Xaut_0871 | Xaut_4294 | TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: acr:Acry_0996 L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: hne:HNE_0171 threonine dehydratase. | 0.922 |
| Xaut_0871 | glyA | Xaut_0871 | Xaut_0870 | TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: acr:Acry_0996 L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.980 |
| Xaut_0871 | glyA-2 | Xaut_0871 | Xaut_4276 | TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: acr:Acry_0996 L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.948 |
| Xaut_1506 | Xaut_0871 | Xaut_1506 | Xaut_0871 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: threonine dehydratase. | TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: acr:Acry_0996 L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.922 |
| Xaut_1506 | Xaut_1660 | Xaut_1506 | Xaut_1660 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: threonine dehydratase. | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: rpc:RPC_3257 phosphoserine phosphatase SerB. | 0.906 |
| Xaut_1506 | Xaut_3208 | Xaut_1506 | Xaut_3208 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: threonine dehydratase. | TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein; KEGG: rpa:RPA3429 serine acetyltransferase. | 0.815 |
| Xaut_1506 | Xaut_4110 | Xaut_1506 | Xaut_4110 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: threonine dehydratase. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bra:BRADO5091 putative threonine dehydratase. | 0.905 |
| Xaut_1506 | Xaut_4294 | Xaut_1506 | Xaut_4294 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: threonine dehydratase. | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: hne:HNE_0171 threonine dehydratase. | 0.920 |
| Xaut_1506 | glyA | Xaut_1506 | Xaut_0870 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: threonine dehydratase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.906 |
| Xaut_1506 | glyA-2 | Xaut_1506 | Xaut_4276 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: threonine dehydratase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.906 |
| Xaut_1660 | Xaut_0871 | Xaut_1660 | Xaut_0871 | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: rpc:RPC_3257 phosphoserine phosphatase SerB. | TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: acr:Acry_0996 L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.914 |
| Xaut_1660 | Xaut_1506 | Xaut_1660 | Xaut_1506 | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: rpc:RPC_3257 phosphoserine phosphatase SerB. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: threonine dehydratase. | 0.906 |