STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Xaut_3449Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1221 aa)    
Predicted Functional Partners:
Xaut_0058
Integral membrane sensor hybrid histidine kinase; PFAM: Na+/solute symporter; response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: rpa:RPA0853 sensor histidine kinase, possible proline sensor PrlS.
  
  
 0.964
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 0.958
Xaut_2428
PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: pde:Pden_5112 integral membrane sensor signal transduction histidine kinase.
  
  
 0.957
Xaut_3506
PFAM: ornithine cyclodeaminase/mu-crystallin; Shikimate/quinate 5-dehydrogenase; KEGG: pol:Bpro_2024 ornithine cyclodeaminase.
  
 
 0.949
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
   
 0.948
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
 0.945
Xaut_0887
PFAM: glutamine synthetase catalytic region; KEGG: mlo:mll5148 probable glutamine synthetase.
   
 
 0.935
Xaut_1141
Glutamate--ammonia ligase; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: sme:SMb20745 putative glutatmine synthetase II protein.
   
 
 0.935
glsA-2
PFAM: cyclic nucleotide-binding; Sulfate transporter/antisigma-factor antagonist STAS; glutaminase; KEGG: bja:bll4798 putative glutaminase; Belongs to the glutaminase family.
  
 
 0.935
Xaut_1939
Glutamate--putrescine ligase; PFAM: glutamine synthetase catalytic region; KEGG: glutamine synthetase family protein.
   
 
 0.935
Your Current Organism:
Xanthobacter autotrophicus
NCBI taxonomy Id: 78245
Other names: X. autotrophicus Py2, Xanthobacter autotrophicus Py2, Xanthobacter autotrophicus str. Py2, Xanthobacter autotrophicus strain Py2, Xanthobacter sp. Py2
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