STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lldDFMN-dependent alpha-hydroxy acid dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. (388 aa)    
Predicted Functional Partners:
Xaut_1422
D-lactate dehydrogenase (cytochrome); PFAM: FAD linked oxidase domain protein; KEGG: rpc:RPC_3276 FAD linked oxidase-like.
 0.951
Xaut_4350
L-lactate transport; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
  
 0.944
Xaut_3143
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic protein domain protein; malic protein NAD-binding; KEGG: bra:BRADO3367 putative bifunctional enzyme: malic oxidoreductase (N-terminal); phosphotransacetylase (C-terminal).
    
 0.937
Xaut_2370
TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: mag:amb3174 pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.932
Xaut_3930
PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: pmy:Pmen_3633 GntR domain protein.
  
 0.917
Xaut_0214
Pyruvate dehydrogenase (acetyl-transferring); Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.913
Xaut_0494
TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; KEGG: rpb:RPB_1099 pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
    
 0.910
Xaut_3937
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); PFAM: malic protein domain protein; malic protein NAD-binding; KEGG: bja:bll6469 malic enzyme.
    
 0.910
Xaut_4304
PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; KEGG: bbt:BBta_2338 putative pyruvate, phosphate dikinase.
    
 0.910
pdhA
Pyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 
 0.903
Your Current Organism:
Xanthobacter autotrophicus
NCBI taxonomy Id: 78245
Other names: X. autotrophicus Py2, Xanthobacter autotrophicus Py2, Xanthobacter autotrophicus str. Py2, Xanthobacter autotrophicus strain Py2, Xanthobacter sp. Py2
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