close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Xaut_4635Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; KEGG: rpa:RPA3882 sensor histidine kinase with multiple PAS and a response regulator receiver domain. (857 aa)    
Predicted Functional Partners:
Xaut_0058
Integral membrane sensor hybrid histidine kinase; PFAM: Na+/solute symporter; response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: rpa:RPA0853 sensor histidine kinase, possible proline sensor PrlS.
 
 
0.965
Xaut_0632
PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: eba:ebA6722 histidine kinase.
 
 
0.965
Xaut_2026
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; KEGG: rsh:Rsph17029_2967 PAS/PAC sensor hybrid histidine kinase.
 
 
0.964
Xaut_3487
KEGG: rpc:RPC_4248 hypothetical protein.
  
 0.953
Xaut_0279
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; KEGG: rpa:RPA0286 putative diguanylate cyclase (GGDEF) with HAMP domain.
 
 0.923
Xaut_2333
Signal transduction histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase dimerisation/phosphoacceptor; KEGG: bra:BRADO3497 putative signal transduction histidine kinase with response regulator receiver domain.
 
 0.908
Xaut_2334
PFAM: response regulator receiver; KEGG: rpc:RPC_2871 response regulator receiver domain protein (CheY-like).
 
 
 0.876
Xaut_3859
PFAM: response regulator receiver; KEGG: nha:Nham_2443 response regulator receiver domain protein (CheY-like).
 
0.875
Xaut_2024
PFAM: response regulator receiver; KEGG: two-component response regulator.
  
 
 0.842
Xaut_4670
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: bja:bll6545 hypothetical protein.
 
 
 0.840
Your Current Organism:
Xanthobacter autotrophicus
NCBI taxonomy Id: 78245
Other names: X. autotrophicus Py2, Xanthobacter autotrophicus Py2, Xanthobacter autotrophicus str. Py2, Xanthobacter autotrophicus strain Py2, Xanthobacter sp. Py2
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.