STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Xaut_4635Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; KEGG: rpa:RPA3882 sensor histidine kinase with multiple PAS and a response regulator receiver domain. (857 aa)    
Predicted Functional Partners:
Xaut_0632
PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: eba:ebA6722 histidine kinase.
 
 
0.975
Xaut_2026
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; KEGG: rsh:Rsph17029_2967 PAS/PAC sensor hybrid histidine kinase.
 
 
0.974
Xaut_0058
Integral membrane sensor hybrid histidine kinase; PFAM: Na+/solute symporter; response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: rpa:RPA0853 sensor histidine kinase, possible proline sensor PrlS.
  
 
 0.962
Xaut_3487
KEGG: rpc:RPC_4248 hypothetical protein.
  
 0.955
Xaut_0279
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; KEGG: rpa:RPA0286 putative diguanylate cyclase (GGDEF) with HAMP domain.
 
 
 0.913
Xaut_2333
Signal transduction histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase dimerisation/phosphoacceptor; KEGG: bra:BRADO3497 putative signal transduction histidine kinase with response regulator receiver domain.
 
 
 0.898
Xaut_2334
PFAM: response regulator receiver; KEGG: rpc:RPC_2871 response regulator receiver domain protein (CheY-like).
 
 
 0.840
Xaut_3859
PFAM: response regulator receiver; KEGG: nha:Nham_2443 response regulator receiver domain protein (CheY-like).
 
 
0.839
Xaut_0082
Transcriptional regulator, NifA, Fis Family; TIGRFAM: Nif-specific regulatory protein; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: rpc:RPC_4475 transcriptional regulator, NifA, fis family.
 
 
 
 0.823
Xaut_3488
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bbt:BBta_6533 two-component cell cycle transcriptional regulator CtrA.
 
 
 0.799
Your Current Organism:
Xanthobacter autotrophicus
NCBI taxonomy Id: 78245
Other names: X. autotrophicus Py2, Xanthobacter autotrophicus Py2, Xanthobacter autotrophicus str. Py2, Xanthobacter autotrophicus strain Py2, Xanthobacter sp. Py2
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.