STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRUM_0791Low molecular weight protein-tyrosine-phosphatase. (167 aa)    
Predicted Functional Partners:
BRUM_1386
Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
  
  0.973
BRUM_0790
Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.
  
 
  0.885
BRUM_1132
Fructosamine kinase.
     0.875
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
    
  0.800
BRUM_0011
Thioredoxin; Belongs to the thioredoxin family.
  
 
 0.710
BRUM_1408
Thioredoxin domain-containing protein.
  
 
 0.710
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
   
   0.651
BRUM_0788
OsmC-like protein.
 
     0.651
ybeY
Putative metalloprotease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
   0.651
rsmH
S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
    
   0.650
Your Current Organism:
Bifidobacterium ruminantium
NCBI taxonomy Id: 78346
Other names: AS 1.2241, ATCC 49390, B. ruminantium, Bifidobacterium ruminatorum, CCUG 34975, DSM 6489, JCM 8222, LMG 12588, LMG:12588, strain Ru687
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