STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRUM_1347Citrate synthase I; Belongs to the citrate synthase family. (430 aa)    
Predicted Functional Partners:
BRUM_0236
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.998
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.987
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.983
BRUM_0994
Isocitrate dehydrogenase, NADP-dependent; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.977
BRUM_0961
Glutamate synthase subunit alpha.
    
 0.973
BRUM_1180
Succinate dehydrogenase, flavoprotein subunit.
  
 0.964
BRUM_1721
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.961
BRUM_1181
Succinate dehydrogenase, iron-sulfur subunit.
  
 0.955
BRUM_1807
NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.941
BRUM_0651
acetyl-/propionyl-CoA carboxylase, alpha subunit.
  
 
 0.921
Your Current Organism:
Bifidobacterium ruminantium
NCBI taxonomy Id: 78346
Other names: AS 1.2241, ATCC 49390, B. ruminantium, Bifidobacterium ruminatorum, CCUG 34975, DSM 6489, JCM 8222, LMG 12588, LMG:12588, strain Ru687
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