STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRUM_1663Phospholipase/carboxylesterase. (260 aa)    
Predicted Functional Partners:
BRUM_0954
Alpha/beta hydrolase.
     
 0.680
BRUM_0890
Hypothetical protein.
  
     0.671
BRUM_0493
Hypothetical protein.
  
     0.652
BRUM_0486
Thiamine biosynthesis lipoprotein, ApbE family; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
  
     0.625
BRUM_0521
Glycerophosphoryl diester phosphodiesterase.
    
 0.598
BRUM_0648
Hypothetical protein.
  
     0.573
BRUM_1835
Aminoglycoside phosphotransferase.
  
     0.561
BRUM_0576
Acyltransferase.
  
  
  0.536
BRUM_0865
Hypothetical protein.
  
     0.532
BRUM_1800
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
   0.525
Your Current Organism:
Bifidobacterium ruminantium
NCBI taxonomy Id: 78346
Other names: AS 1.2241, ATCC 49390, B. ruminantium, Bifidobacterium ruminatorum, CCUG 34975, DSM 6489, JCM 8222, LMG 12588, LMG:12588, strain Ru687
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