STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AK830_g11329S5A_REDUCTASE domain-containing protein. (308 aa)    
Predicted Functional Partners:
AK830_g444
Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.
   
 0.958
AK830_g5008
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]
   
 0.941
AK830_g5106
APH domain-containing protein.
   
 0.926
AK830_g4962
Elongation of fatty acids protein.
    
 0.880
AK830_g7208
APH domain-containing protein.
   
 0.877
AK830_g3708
Uncharacterized protein.
   
 0.877
AK830_g4295
APH domain-containing protein.
   
 0.877
AK830_g11350
BZIP domain-containing protein.
   
 0.866
AK830_g10431
BZIP domain-containing protein.
   
 0.866
AK830_g6087
BZIP domain-containing protein.
   
 0.866
Your Current Organism:
Neonectria ditissima
NCBI taxonomy Id: 78410
Other names: Cylindrocarpon willkommii, N. ditissima, Nectria ditissima
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.