STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AK830_g2453Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (459 aa)    
Predicted Functional Partners:
AK830_g5351
Tryptophan synthase.
  
 
 0.848
AK830_g12258
Acyl-CoA synthetase short-chain family member 3, mitochondrial.
   
 0.840
AK830_g3086
4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.835
AK830_g565
4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.834
AK830_g5263
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.830
AK830_g10253
Glutamate decarboxylase; Belongs to the group II decarboxylase family.
   
 0.828
AK830_g5709
Uncharacterized protein.
   
 0.826
AK830_g602
Uncharacterized protein.
    
  0.822
NTH1
Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
  
 0.820
AK830_g10743
NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.820
Your Current Organism:
Neonectria ditissima
NCBI taxonomy Id: 78410
Other names: Cylindrocarpon willkommii, N. ditissima, Nectria ditissima
Server load: low (28%) [HD]