STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCMIP00000001382Iso_dh domain-containing protein. (402 aa)    
Predicted Functional Partners:
idh3a
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
0.990
aco2
Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.
  
 0.924
cs
Citrate synthase; Belongs to the citrate synthase family.
  
 0.822
mdh2
Malate dehydrogenase, mitochondrial-like protein; Belongs to the LDH/MDH superfamily.
  
 0.817
atp5f1c
ATP synthase subunit gamma.
  
 
 0.801
hmgcl
Pyruvate carboxyltransferase domain-containing protein.
  
 0.773
hmgcll1
Pyruvate carboxyltransferase domain-containing protein.
  
 0.773
SUCLG1
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.
  
 
 0.765
dld
Dihydrolipoyl dehydrogenase.
  
 0.760
ogdhl
Transket_pyr domain-containing protein.
  
 0.726
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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