Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103191276Corticosteroid 11-beta-dehydrogenase isozyme 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (385 aa)    
Predicted Functional Partners:
hsd17b3
Testosterone 17-beta-dehydrogenase 3.
  
  
 0.992
dhrs11
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.984
LOC103186779
Uncharacterized protein.
    
 0.955
hsd11b1
Hydroxysteroid (11-beta) dehydrogenase 1.
  
 
0.947
srd5a3
S5A_REDUCTASE domain-containing protein.
     
 0.945
hsd17b12
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
0.939
LOC103180179
3 beta-hydroxysteroid dehydrogenase; Belongs to the 3-beta-HSD family.
   
 
 0.937
hsd17b7
Hydroxysteroid (17-beta) dehydrogenase 7.
     
 0.935
srd5a1
3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)).
   
 
 0.933
LOC103177103
Uncharacterized protein; Belongs to the cytochrome P450 family.
   
 0.933
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
Server load: low (14%) [HD]