Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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[Homology]
Score
dbtDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (523 aa)    
Predicted Functional Partners:
dld
Dihydrolipoyl dehydrogenase.
 
 0.999
bckdhb
Transket_pyr domain-containing protein.
 
 0.998
ENSCMIP00000006836
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 0.992
ppm1k
PPM-type phosphatase domain-containing protein.
    
 0.986
ivd
Uncharacterized protein.
   
 0.975
pccb
Uncharacterized protein.
  
 
 0.971
LOC103186998
Uncharacterized protein.
  
 0.961
aldh6a1
Aldedh domain-containing protein.
   
 
 0.957
acadsb
Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial-like protein.
   
 0.953
acads
Uncharacterized protein.
   
 0.953
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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