LOC103191283 protein (Callorhinchus milii) - STRING interaction network

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LOC103191283

Nudix hydrolase domain-containing protein. (192 aa)

Predicted Functional Partners:

nme4

0.909

itpa

0.908

LOC103174276

0.903

gmpr

0.903

nt5c

0.901

ampd1

0.901

nt5m

0.901

nme3

0.901

LOC103188966

0.901

LOC103173731

0.900

Your Current Organism:

Callorhinchus milii

NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103173731	LOC103174276	ENSCMIP00000004095	ENSCMIP00000002029	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	IMPDH domain-containing protein.	0.953
LOC103173731	LOC103191283	ENSCMIP00000004095	ENSCMIP00000002326	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Nudix hydrolase domain-containing protein.	0.900
LOC103173731	ampd1	ENSCMIP00000004095	ENSCMIP00000012658	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	0.930
LOC103173731	gmpr	ENSCMIP00000004095	ENSCMIP00000029217	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	0.953
LOC103173731	itpa	ENSCMIP00000004095	ENSCMIP00000045591	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	0.944
LOC103173731	nt5c	ENSCMIP00000004095	ENSCMIP00000001407	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Uncharacterized protein.	0.702
LOC103173731	nt5m	ENSCMIP00000004095	ENSCMIP00000017531	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	Uncharacterized protein.	0.702
LOC103174276	LOC103173731	ENSCMIP00000002029	ENSCMIP00000004095	IMPDH domain-containing protein.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.953
LOC103174276	LOC103191283	ENSCMIP00000002029	ENSCMIP00000002326	IMPDH domain-containing protein.	Nudix hydrolase domain-containing protein.	0.903
LOC103174276	ampd1	ENSCMIP00000002029	ENSCMIP00000012658	IMPDH domain-containing protein.	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	0.934
LOC103174276	gmpr	ENSCMIP00000002029	ENSCMIP00000029217	IMPDH domain-containing protein.	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	0.901
LOC103174276	itpa	ENSCMIP00000002029	ENSCMIP00000045591	IMPDH domain-containing protein.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	0.930
LOC103174276	nt5c	ENSCMIP00000002029	ENSCMIP00000001407	IMPDH domain-containing protein.	Uncharacterized protein.	0.925
LOC103174276	nt5m	ENSCMIP00000002029	ENSCMIP00000017531	IMPDH domain-containing protein.	Uncharacterized protein.	0.925
LOC103188966	LOC103191283	ENSCMIP00000038274	ENSCMIP00000002326	Nucleoside diphosphate kinase.	Nudix hydrolase domain-containing protein.	0.901
LOC103188966	itpa	ENSCMIP00000038274	ENSCMIP00000045591	Nucleoside diphosphate kinase.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	0.948
LOC103188966	nme3	ENSCMIP00000038274	ENSCMIP00000019806	Nucleoside diphosphate kinase.	Nucleoside diphosphate kinase.	0.901
LOC103188966	nme4	ENSCMIP00000038274	ENSCMIP00000018677	Nucleoside diphosphate kinase.	NDK domain-containing protein; Belongs to the NDK family.	0.950
LOC103191283	LOC103173731	ENSCMIP00000002326	ENSCMIP00000004095	Nudix hydrolase domain-containing protein.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.900
LOC103191283	LOC103174276	ENSCMIP00000002326	ENSCMIP00000002029	Nudix hydrolase domain-containing protein.	IMPDH domain-containing protein.	0.903