Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSCMIP00000002348SH2 domain-containing protein. (111 aa)    
Predicted Functional Partners:
insr
Tyrosine-protein kinase receptor.
    
  0.912
eloc
Skp1_POZ domain-containing protein; Belongs to the SKP1 family.
    
 0.650
cul5
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.593
elob
Ubiquitin-like domain-containing protein.
    
 0.591
ENSCMIP00000004047
Uncharacterized protein.
  
  
 
0.572
pik3r2
Uncharacterized protein.
    
 
0.568
pik3r3
Uncharacterized protein.
    
 
0.568
pik3r1
Uncharacterized protein.
    
 
0.568
cish
Uncharacterized protein.
  
  
 
0.554
Socs2
Uncharacterized protein.
  
  
 
0.552
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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