spcs2 protein (Callorhinchus milii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

spcs2

Uncharacterized protein. (204 aa)

Predicted Functional Partners:

spcs3

0.999

spcs1

0.999

sec11a

0.984

grp

0.967

sec63

0.928

samd7

0.924

eri3

0.909

ddost

0.901

hspa5

0.888

trappc4

0.863

Your Current Organism:

Callorhinchus milii

NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ddost	hspa5	ENSCMIP00000016070	ENSCMIP00000008220	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.661
ddost	sec63	ENSCMIP00000016070	ENSCMIP00000035852	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]	Translocation protein SEC63-like protein.	0.849
ddost	spcs1	ENSCMIP00000016070	ENSCMIP00000018314	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]	Uncharacterized protein.	0.605
ddost	spcs2	ENSCMIP00000016070	ENSCMIP00000002557	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]	Uncharacterized protein.	0.901
ddost	spcs3	ENSCMIP00000016070	ENSCMIP00000005417	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]	Signal peptidase complex subunit 3.	0.660
eri3	spcs2	ENSCMIP00000023034	ENSCMIP00000002557	Exonuclease domain-containing protein.	Uncharacterized protein.	0.909
eri3	trappc4	ENSCMIP00000023034	ENSCMIP00000017932	Exonuclease domain-containing protein.	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	0.907
grp	hspa5	ENSCMIP00000015939	ENSCMIP00000008220	Gastrin-releasing peptide.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.404
grp	sec63	ENSCMIP00000015939	ENSCMIP00000035852	Gastrin-releasing peptide.	Translocation protein SEC63-like protein.	0.553
grp	spcs1	ENSCMIP00000015939	ENSCMIP00000018314	Gastrin-releasing peptide.	Uncharacterized protein.	0.956
grp	spcs2	ENSCMIP00000015939	ENSCMIP00000002557	Gastrin-releasing peptide.	Uncharacterized protein.	0.967
grp	spcs3	ENSCMIP00000015939	ENSCMIP00000005417	Gastrin-releasing peptide.	Signal peptidase complex subunit 3.	0.963
hspa5	ddost	ENSCMIP00000008220	ENSCMIP00000016070	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]	0.661
hspa5	grp	ENSCMIP00000008220	ENSCMIP00000015939	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Gastrin-releasing peptide.	0.404
hspa5	samd7	ENSCMIP00000008220	ENSCMIP00000022547	Uncharacterized protein; Belongs to the heat shock protein 70 family.	SAM domain-containing protein.	0.735
hspa5	sec11a	ENSCMIP00000008220	ENSCMIP00000010321	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Signal peptidase complex catalytic subunit SEC11.	0.404
hspa5	sec63	ENSCMIP00000008220	ENSCMIP00000035852	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Translocation protein SEC63-like protein.	0.961
hspa5	spcs1	ENSCMIP00000008220	ENSCMIP00000018314	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.590
hspa5	spcs2	ENSCMIP00000008220	ENSCMIP00000002557	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.888
hspa5	spcs3	ENSCMIP00000008220	ENSCMIP00000005417	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Signal peptidase complex subunit 3.	0.555