STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCMIP00000002648Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (176 aa)    
Predicted Functional Partners:
oat
Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.726
aldh4a1
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
  
 0.717
aldh18a1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
   
 
 0.693
COX2
Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.
    
 0.638
COX3
Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex.
    
 0.624
COX1
Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
   
 0.590
cs
Citrate synthase; Belongs to the citrate synthase family.
   
  
 0.587
aldh5a1
Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.527
crym
Uncharacterized protein.
  
  
 0.455
glud1
ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
  
 0.454
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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