Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rnf41Uncharacterized protein. (317 aa)    
Predicted Functional Partners:
birc6
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.970
vps52
Uncharacterized protein.
    
 
 0.963
asb6
Uncharacterized protein.
    
 0.962
usp8
Uncharacterized protein; Belongs to the peptidase C19 family.
    
 0.945
usp50
USP domain-containing protein; Belongs to the peptidase C19 family.
    
 0.945
ttc1
TPR_REGION domain-containing protein.
    
   0.918
enoph1
Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
    
   0.917
smurf1
E3 ubiquitin-protein ligase.
    
 0.914
smurf2
E3 ubiquitin-protein ligase.
    
 0.914
egfr
Receptor protein-tyrosine kinase.
    
 0.913
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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