Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC103173716Exonuclease domain-containing protein. (249 aa)    
Predicted Functional Partners:
pan3
PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...]
  
 
 0.991
pan2
USP domain-containing protein.
 
  
  0.964
LOC103172817
USP domain-containing protein.
 
   
  0.952
tnrc6a
TNRC6-PABC_bdg domain-containing protein.
    
 
 0.746
tnrc6c
Uncharacterized protein.
    
 
 0.746
exosc10
HRDC domain-containing protein.
   
 0.728
exosc4
Uncharacterized protein.
  
 
 0.660
ENSCMIP00000004830
Uncharacterized protein.
  
 
 0.660
dis3
Uncharacterized protein; Belongs to the RNR ribonuclease family.
   
 
 0.645
dis3l
RNB domain-containing protein; Belongs to the RNR ribonuclease family.
   
 
 0.645
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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