Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cdc42se1CRIB domain-containing protein. (72 aa)    
Predicted Functional Partners:
cdc42ep4
CRIB domain-containing protein.
      
 0.837
baiap2l1
Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1.
      
 0.752
cdc42
Cell division control protein 42-like protein.
    
 
 0.694
pnpla4
PNPLA domain-containing protein.
      
 0.692
cdc42ep3
Cdc42 effector protein 3-like protein.
      
 0.691
flii
Uncharacterized protein.
      
 0.673
tmed2
GOLD domain-containing protein.
      
 0.661
baiap2
Uncharacterized protein.
      
 0.611
creb3
BZIP domain-containing protein.
   
  
 0.604
ENSCMIP00000014728
Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family.
      
 0.518
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
Server load: medium (50%) [HD]