STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
retProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1086 aa)    
Predicted Functional Partners:
nrtn
TGF_BETA_2 domain-containing protein.
    
 0.970
Gdnf
TGF_BETA_2 domain-containing protein.
    
 0.969
gfra1
GDNF family receptor alpha; Belongs to the GDNFR family.
    
 0.887
Gfral
Uncharacterized protein.
    
 0.859
ENSCMIP00000039932
GDNF domain-containing protein.
    
 0.859
dok1
IRS-type PTB domain-containing protein.
    
  0.836
ENSCMIP00000029724
Uncharacterized protein.
    
  0.836
ENSCMIP00000009079
TGF_BETA_2 domain-containing protein.
     
 0.804
grb2
Uncharacterized protein.
   
 0.787
ENSCMIP00000047424
Uncharacterized protein.
    
 0.734
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.