Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cfl2Cofilin 2; Belongs to the actin-binding proteins ADF family. (163 aa)    
Predicted Functional Partners:
limk1
Uncharacterized protein.
   
 0.974
limk2
Uncharacterized protein.
   
 0.974
ssh2
Uncharacterized protein.
    
 0.964
actg1
Uncharacterized protein.
   
 0.950
LOC103179244
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
  
  
 
0.904
LOC103191033
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
  
  
 
0.902
wdr1
WD_REPEATS_REGION domain-containing protein.
   
 
 0.828
capzb
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.749
pfn4
Profilin; Belongs to the profilin family.
   
 0.742
cap1
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.693
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.