Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gpha2Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (134 aa)    
Predicted Functional Partners:
gphb5
Cys_knot domain-containing protein.
    
 0.997
unc79
Uncharacterized protein.
    
 0.681
ENSCMIP00000005327
G_PROTEIN_RECEP_F1_2 domain-containing protein.
    
 0.676
LOC103186140
Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
    
 0.676
TSHR
Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
    
 0.676
tshb
Thyroid-stimulating hormone beta subunit 2.
    
 0.651
LOC103179889
Thyroid-stimulating hormone beta subunit 1.
    
 0.651
LOC103173596
Uncharacterized protein.
      
 0.619
klhl28
BTB domain-containing protein.
     
 0.598
prelid2
PRELI domain-containing protein 2.
      
 0.587
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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