Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tp53bp2Uncharacterized protein. (1099 aa)    
Predicted Functional Partners:
ppp1cc
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 
 0.764
ppp1cb
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 
 0.756
mapre1
Uncharacterized protein.
    
   0.749
il10
Uncharacterized protein.
    
 0.708
il10ra
Uncharacterized protein.
   
 0.708
LOC103179443
Uncharacterized protein.
    
 0.644
LOC103174534
P53 domain-containing protein.
    
 0.641
ENSCMIP00000006076
P53 domain-containing protein.
    
 0.641
LOC103172820
Uncharacterized protein.
    
 0.641
tp73
Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
    
 0.641
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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