Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
mknk1MAP kinase-interacting serine/threonine-protein kinase 1; Belongs to the protein kinase superfamily. (473 aa)    
Predicted Functional Partners:
mapk1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
0.975
eif4e1b
Eukaryotic translation initiation factor 4E-like protein; Belongs to the eukaryotic initiation factor 4E family.
    
 0.960
LOC103182130
Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family.
    
 0.960
LOC103182199
Eukaryotic translation initiation factor 4E family member 1c; Belongs to the eukaryotic initiation factor 4E family.
    
 0.958
LOC103189775
BZIP domain-containing protein.
     
 0.902
mknk2
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
  
  
 
0.901
eif4e2
Eukaryotic translation initiation factor 4E type 2-like protein; Belongs to the eukaryotic initiation factor 4E family.
     
  0.900
dcx
Doublecortin.
 
      0.659
dglucy
DUF4392 domain-containing protein.
      
 0.585
ppp2r1a
Uncharacterized protein.
   
 
 0.489
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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