Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
spcs3Signal peptidase complex subunit 3. (180 aa)    
Predicted Functional Partners:
spcs2
Uncharacterized protein.
   
 0.999
spcs1
Uncharacterized protein.
   
 0.999
sec11a
Signal peptidase complex catalytic subunit SEC11.
   
 0.982
grp
Gastrin-releasing peptide.
   
 0.963
sec63
Translocation protein SEC63-like protein.
    
 
 0.923
immp2l
Mitochondrial inner membrane protease subunit.
   
 0.832
immp1l
Mitochondrial inner membrane protease subunit.
   
 0.832
mrps18b
Uncharacterized protein.
      
 0.692
ddost
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]
   
 0.660
auh
AU RNA-binding protein/enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
 
      0.658
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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