Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nficNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (612 aa)    
Predicted Functional Partners:
nkx2-1
Homeobox domain-containing protein.
    
 
 0.579
Nkx2-5
Homeobox domain-containing protein.
    
 
 0.562
stx6
t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.
      
 0.509
tal1
BHLH domain-containing protein.
      
 0.499
tm2d1
TM2 domain-containing protein.
      
 0.498
nf1
Uncharacterized protein.
      
 0.495
ctcf
Uncharacterized protein.
    
 
 0.494
LOC103176643
Uncharacterized protein; Belongs to the semaphorin family.
      
 0.458
vdac1
Uncharacterized protein.
      
 0.418
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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