STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psen2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (461 aa)    
Predicted Functional Partners:
aph1b
Gamma-secretase subunit Aph-1b-like protein.
   
 0.958
LOC103181020
Uncharacterized protein.
   
 0.958
notch2
Uncharacterized protein.
    
 0.914
ENSCMIP00000022787
Uncharacterized protein.
   
 0.911
psen1
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
  
  
0.902
ENSCMIP00000025170
Uncharacterized protein.
   
 0.799
app
BPTI/Kunitz inhibitor domain-containing protein.
    
 
 0.718
gsk3b
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.612
ctnnb1
Uncharacterized protein.
    
 
 0.582
aplp2
Amyloid-like protein 2.
    
 
 0.567
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.