LOC103181379 protein (Callorhinchus milii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

LOC103181379

Guanylin-like protein. (106 aa)

Predicted Functional Partners:

LOC103172632

0.915

LOC103172259

0.915

tmigd1

0.832

npr3

0.624

LOC103184961

0.587

Susd5

0.570

tmem108

0.553

ENSCMIP00000015308

0.508

cftr

0.468

tmem52

0.440

Your Current Organism:

Callorhinchus milii

NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCMIP00000015308	LOC103172259	ENSCMIP00000015308	ENSCMIP00000007135	PDZ domain-containing protein.	Guanylate cyclase domain-containing protein.	0.618
ENSCMIP00000015308	LOC103172632	ENSCMIP00000015308	ENSCMIP00000005171	PDZ domain-containing protein.	Uncharacterized protein.	0.618
ENSCMIP00000015308	LOC103181379	ENSCMIP00000015308	ENSCMIP00000005681	PDZ domain-containing protein.	Guanylin-like protein.	0.508
ENSCMIP00000015308	cftr	ENSCMIP00000015308	ENSCMIP00000024575	PDZ domain-containing protein.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	0.518
LOC103172259	ENSCMIP00000015308	ENSCMIP00000007135	ENSCMIP00000015308	Guanylate cyclase domain-containing protein.	PDZ domain-containing protein.	0.618
LOC103172259	LOC103172632	ENSCMIP00000007135	ENSCMIP00000005171	Guanylate cyclase domain-containing protein.	Uncharacterized protein.	0.900
LOC103172259	LOC103181379	ENSCMIP00000007135	ENSCMIP00000005681	Guanylate cyclase domain-containing protein.	Guanylin-like protein.	0.915
LOC103172259	cftr	ENSCMIP00000007135	ENSCMIP00000024575	Guanylate cyclase domain-containing protein.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	0.483
LOC103172259	npr3	ENSCMIP00000007135	ENSCMIP00000030051	Guanylate cyclase domain-containing protein.	ANF_receptor domain-containing protein.	0.551
LOC103172632	ENSCMIP00000015308	ENSCMIP00000005171	ENSCMIP00000015308	Uncharacterized protein.	PDZ domain-containing protein.	0.618
LOC103172632	LOC103172259	ENSCMIP00000005171	ENSCMIP00000007135	Uncharacterized protein.	Guanylate cyclase domain-containing protein.	0.900
LOC103172632	LOC103181379	ENSCMIP00000005171	ENSCMIP00000005681	Uncharacterized protein.	Guanylin-like protein.	0.915
LOC103172632	cftr	ENSCMIP00000005171	ENSCMIP00000024575	Uncharacterized protein.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	0.483
LOC103172632	npr3	ENSCMIP00000005171	ENSCMIP00000030051	Uncharacterized protein.	ANF_receptor domain-containing protein.	0.422
LOC103181379	ENSCMIP00000015308	ENSCMIP00000005681	ENSCMIP00000015308	Guanylin-like protein.	PDZ domain-containing protein.	0.508
LOC103181379	LOC103172259	ENSCMIP00000005681	ENSCMIP00000007135	Guanylin-like protein.	Guanylate cyclase domain-containing protein.	0.915
LOC103181379	LOC103172632	ENSCMIP00000005681	ENSCMIP00000005171	Guanylin-like protein.	Uncharacterized protein.	0.915
LOC103181379	LOC103184961	ENSCMIP00000005681	ENSCMIP00000022354	Guanylin-like protein.	Alpha-carbonic anhydrase domain-containing protein; Belongs to the alpha-carbonic anhydrase family.	0.587
LOC103181379	Susd5	ENSCMIP00000005681	ENSCMIP00000035471	Guanylin-like protein.	Uncharacterized protein.	0.570
LOC103181379	cftr	ENSCMIP00000005681	ENSCMIP00000024575	Guanylin-like protein.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	0.468