Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prpf39Uncharacterized protein. (674 aa)    
Predicted Functional Partners:
snrnp70
U1 small nuclear ribonucleoprotein 70 kDa.
   
 0.951
SNRPC
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]
   
 0.941
snrpf
Sm domain-containing protein.
    
 0.914
rbm25
Uncharacterized protein.
   
 
 0.894
sf3b1
TOG domain-containing protein.
   
 
 0.889
LOC103183390
tRNA selenocysteine 1-associated protein 1-like protein.
   
 
 0.883
trnau1ap
Uncharacterized protein.
   
 
 0.883
cdc5l
Cell division cycle 5-like protein.
   
 
 0.877
pnisr
Uncharacterized protein.
   
  
 0.877
snrpa1
LRRcap domain-containing protein.
    
 
 0.874
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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