Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ap4s1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (144 aa)    
Predicted Functional Partners:
ap4b1
AP complex subunit beta; Belongs to the adaptor complexes large subunit family.
   
 0.999
ap4e1
AP-4 complex subunit epsilon; AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system; Belongs to the adaptor complexes large subunit family.
   
 0.999
ENSCMIP00000020775
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
   
 0.981
tepsin
ENTH domain-containing protein.
   
 
 0.975
daglb
Lipase_3 domain-containing protein.
   
  
 0.915
LOC103190656
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
      
 0.914
rusc2
RUN domain-containing protein.
   
  
 0.907
ENSCMIP00000010120
Uncharacterized protein.
   
  
 0.884
ENSCMIP00000002072
Uncharacterized protein.
   
 0.825
LOC103174622
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
   
 0.825
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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