eml5 protein (Callorhinchus milii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

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Co-occurrence

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Experiments

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[Homology]

Score

eml5

Uncharacterized protein. (1973 aa)

Predicted Functional Partners:

crtc3

0.588

mis12

0.555

ranbp2

0.537

ENSCMIP00000004712

0.511

ift140

0.503

top3b

0.472

mad1l1

0.456

Ak9

0.449

ENSCMIP00000035595

0.449

mysm1

0.449

Your Current Organism:

Callorhinchus milii

NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ak9	ENSCMIP00000035595	ENSCMIP00000035587	ENSCMIP00000035595	Uncharacterized protein.	Uncharacterized protein.	0.999
Ak9	eml5	ENSCMIP00000035587	ENSCMIP00000006344	Uncharacterized protein.	Uncharacterized protein.	0.449
ENSCMIP00000004712	eml5	ENSCMIP00000004712	ENSCMIP00000006344	RanBD1 domain-containing protein.	Uncharacterized protein.	0.511
ENSCMIP00000004712	mad1l1	ENSCMIP00000004712	ENSCMIP00000026893	RanBD1 domain-containing protein.	Mitotic spindle assembly checkpoint protein MAD1-like protein.	0.544
ENSCMIP00000004712	mysm1	ENSCMIP00000004712	ENSCMIP00000047519	RanBD1 domain-containing protein.	Uncharacterized protein.	0.577
ENSCMIP00000004712	ranbp2	ENSCMIP00000004712	ENSCMIP00000038177	RanBD1 domain-containing protein.	Uncharacterized protein.	0.595
ENSCMIP00000035595	Ak9	ENSCMIP00000035595	ENSCMIP00000035587	Uncharacterized protein.	Uncharacterized protein.	0.999
ENSCMIP00000035595	eml5	ENSCMIP00000035595	ENSCMIP00000006344	Uncharacterized protein.	Uncharacterized protein.	0.449
crtc3	eml5	ENSCMIP00000022206	ENSCMIP00000006344	Uncharacterized protein.	Uncharacterized protein.	0.588
eml5	Ak9	ENSCMIP00000006344	ENSCMIP00000035587	Uncharacterized protein.	Uncharacterized protein.	0.449
eml5	ENSCMIP00000004712	ENSCMIP00000006344	ENSCMIP00000004712	Uncharacterized protein.	RanBD1 domain-containing protein.	0.511
eml5	ENSCMIP00000035595	ENSCMIP00000006344	ENSCMIP00000035595	Uncharacterized protein.	Uncharacterized protein.	0.449
eml5	crtc3	ENSCMIP00000006344	ENSCMIP00000022206	Uncharacterized protein.	Uncharacterized protein.	0.588
eml5	ift140	ENSCMIP00000006344	ENSCMIP00000019050	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.503
eml5	mad1l1	ENSCMIP00000006344	ENSCMIP00000026893	Uncharacterized protein.	Mitotic spindle assembly checkpoint protein MAD1-like protein.	0.456
eml5	mis12	ENSCMIP00000006344	ENSCMIP00000027832	Uncharacterized protein.	Uncharacterized protein.	0.555
eml5	mysm1	ENSCMIP00000006344	ENSCMIP00000047519	Uncharacterized protein.	Uncharacterized protein.	0.449
eml5	ranbp2	ENSCMIP00000006344	ENSCMIP00000038177	Uncharacterized protein.	Uncharacterized protein.	0.537
eml5	top3b	ENSCMIP00000006344	ENSCMIP00000012230	Uncharacterized protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.472
ift140	eml5	ENSCMIP00000019050	ENSCMIP00000006344	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.503