Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dot1lHistone-lysine N-methyltransferase, H3 lysine-79 specific. (1742 aa)    
Predicted Functional Partners:
setd2
Uncharacterized protein.
   
 0.980
ezh2
Uncharacterized protein.
   
 0.966
ehmt1
Uncharacterized protein.
   
 0.954
smyd2
Uncharacterized protein.
   
 0.953
Smyd3
SET domain-containing protein.
   
 0.953
LOC103173106
Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
   
 0.946
smyd1
Uncharacterized protein.
   
 0.937
camkmt
Uncharacterized protein.
     
 0.936
prdm2
PR domain zinc finger protein 2.
     
 0.930
tfb2m
rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
      
 0.921
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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