Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
alplAlkaline phosphatase. (537 aa)    
Predicted Functional Partners:
acp1
LMWPc domain-containing protein.
    
 0.919
LOC103184426
Alkaline phosphatase.
  
  
 
0.902
Pts
6-pyruvoyl tetrahydrobiopterin synthase-like protein.
     
  0.900
LOC103180820
GTP_cyclohydroI domain-containing protein.
     
  0.900
gch1
GTP_cyclohydroI domain-containing protein.
     
  0.900
tpk1
Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family.
     
  0.900
trip11
GRIP domain-containing protein.
   
 0.642
spcs2
Uncharacterized protein.
   
   0.624
bdnf
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
      
 0.566
agxt
Serine--pyruvate aminotransferase.
     
 0.536
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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