Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hand2BHLH domain-containing protein. (212 aa)    
Predicted Functional Partners:
Nkx2-5
Homeobox domain-containing protein.
   
 0.813
smyd1
Uncharacterized protein.
    
 0.803
vcl
Uncharacterized protein.
      
 0.793
tbx5
Uncharacterized protein.
    
 0.784
hoxd13
Homeobox protein HoxD13.
    
 
 0.783
tbx20
T-box transcription factor TBX20.
   
 
 0.764
nkx2-3
Homeobox domain-containing protein.
    
 0.701
Phox2b
Homeobox domain-containing protein.
   
 
 0.700
mef2c
Myocyte-specific enhancer factor 2C-like protein.
    
 0.689
calhm3
Uncharacterized protein.
   
  
 0.682
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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