Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
trmt5tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. (496 aa)    
Predicted Functional Partners:
tyw5
JmjC domain-containing protein.
      
 0.863
dus2
DRBM domain-containing protein.
   
  
 0.799
pstpip2
Proline-serine-threonine phosphatase-interacting protein 2-like protein.
    
   0.794
tyw3
TYW3 domain-containing protein.
  
 
 0.782
ENSCMIP00000028713
Flavodoxin-like domain-containing protein.
   
 
 0.778
senp8
ULP_PROTEASE domain-containing protein.
    
   0.751
trmt10c
SAM-dependent MTase TRM10-type domain-containing protein.
   
  
 0.727
trmt11
UPF0020 domain-containing protein.
   
  
 0.720
LOC103188744
RNA (Guanine-9-)-methyltransferase domain-containing protein 2-like protein.
   
  
 0.717
dus1l
Uncharacterized protein.
   
  
 0.717
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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