Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ptf1aBHLH domain-containing protein. (261 aa)    
Predicted Functional Partners:
rbpjl
Uncharacterized protein.
   
 0.902
rbpj
Uncharacterized protein.
   
 0.865
Barhl1
Uncharacterized protein.
      
 0.740
pdx1
Homeobox domain-containing protein.
    
 
 0.730
nkx2-2
Homeobox domain-containing protein.
    
 0.693
hnf1b
Homeobox domain-containing protein.
     
 0.685
ins
Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
      
 0.675
hnf1a
Homeobox domain-containing protein.
     
 0.657
ENSCMIP00000037561
Homeobox domain-containing protein.
    
 
 0.628
foxn4
Fork-head domain-containing protein.
    
 
 0.624
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
Server load: low (40%) [HD]