Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSCMIP00000006795Ion_trans domain-containing protein. (127 aa)    
Predicted Functional Partners:
ENSCMIP00000004965
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
 
  
  0.970
LOC103188289
Uncharacterized protein.
 
  
 
0.955
unc79
Uncharacterized protein.
   
 0.865
ENSCMIP00000013773
Ig-like domain-containing protein.
    
 0.791
scn3b
Ig-like domain-containing protein.
   
 0.748
ENSCMIP00000017628
Ion_trans domain-containing protein.
  
 0.682
Scn2b
IGv domain-containing protein.
   
 0.668
ENSCMIP00000003951
Uncharacterized protein.
   
 0.608
ENSCMIP00000017631
Ion_trans domain-containing protein.
   
 0.608
LOC103177883
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
  
  
 
0.564
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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