| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSCMIP00000006806 | SUCLG1 | ENSCMIP00000006806 | ENSCMIP00000030110 | Uncharacterized protein. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.668 |
| ENSCMIP00000006806 | aco2 | ENSCMIP00000006806 | ENSCMIP00000010380 | Uncharacterized protein. | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | 0.639 |
| ENSCMIP00000006806 | atp5f1a | ENSCMIP00000006806 | ENSCMIP00000020919 | Uncharacterized protein. | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. | 0.708 |
| ENSCMIP00000006806 | clpp | ENSCMIP00000006806 | ENSCMIP00000011361 | Uncharacterized protein. | ATP-dependent Clp protease proteolytic subunit. | 0.710 |
| ENSCMIP00000006806 | cs | ENSCMIP00000006806 | ENSCMIP00000022667 | Uncharacterized protein. | Citrate synthase; Belongs to the citrate synthase family. | 0.702 |
| ENSCMIP00000006806 | hadh | ENSCMIP00000006806 | ENSCMIP00000015323 | Uncharacterized protein. | Uncharacterized protein. | 0.795 |
| ENSCMIP00000006806 | hadha | ENSCMIP00000006806 | ENSCMIP00000013219 | Uncharacterized protein. | Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.628 |
| ENSCMIP00000006806 | pdhb | ENSCMIP00000006806 | ENSCMIP00000038366 | Uncharacterized protein. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.668 |
| ENSCMIP00000006806 | sdha | ENSCMIP00000006806 | ENSCMIP00000036903 | Uncharacterized protein. | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.711 |
| ENSCMIP00000006806 | suclg2 | ENSCMIP00000006806 | ENSCMIP00000014033 | Uncharacterized protein. | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.631 |
| SUCLG1 | ENSCMIP00000006806 | ENSCMIP00000030110 | ENSCMIP00000006806 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Uncharacterized protein. | 0.668 |
| SUCLG1 | aco2 | ENSCMIP00000030110 | ENSCMIP00000010380 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | 0.963 |
| SUCLG1 | atp5f1a | ENSCMIP00000030110 | ENSCMIP00000020919 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. | 0.889 |
| SUCLG1 | clpp | ENSCMIP00000030110 | ENSCMIP00000011361 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | ATP-dependent Clp protease proteolytic subunit. | 0.586 |
| SUCLG1 | cs | ENSCMIP00000030110 | ENSCMIP00000022667 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Citrate synthase; Belongs to the citrate synthase family. | 0.957 |
| SUCLG1 | hadh | ENSCMIP00000030110 | ENSCMIP00000015323 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Uncharacterized protein. | 0.483 |
| SUCLG1 | hadha | ENSCMIP00000030110 | ENSCMIP00000013219 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.532 |
| SUCLG1 | pdhb | ENSCMIP00000030110 | ENSCMIP00000038366 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.825 |
| SUCLG1 | sdha | ENSCMIP00000030110 | ENSCMIP00000036903 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.998 |
| SUCLG1 | suclg2 | ENSCMIP00000030110 | ENSCMIP00000014033 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.999 |