Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103189177Signal transducer and activator of transcription. (787 aa)    
Predicted Functional Partners:
LOC103181975
Tyrosine-protein kinase.
   
 0.975
jak2
Tyrosine-protein kinase.
   
 0.973
jak1
Tyrosine-protein kinase.
   
 0.968
tyk2
Tyrosine-protein kinase.
   
 0.962
erbb3
Protein kinase domain-containing protein.
    
 0.960
erbb4
Receptor protein-tyrosine kinase.
    
 0.960
egfr
Receptor protein-tyrosine kinase.
    
 0.960
stat3
Signal transducer and activator of transcription.
   
0.957
ep300
Uncharacterized protein.
    
 0.838
crebbp
Uncharacterized protein.
    
 0.806
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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